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JNK-IN-8
- 英文名称：JNK-IN-8
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11401
- cas：1410880-22-6
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-04-30
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11401 |
| 用途 | 科研检测 |
| 英文名称 | JNK-IN-8 |
| 包装规格 | 1MG |
| CAS编号 | 1410880-22-6 |
| 别名 | JNK-IN-8 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C29H29N7O2
分子量:507.6
溶剂:DMSO (45 mg/ml)
性状:Pale yellow solid
存储:-20°C
Activity (short version):JNK inhibitor
Function / Pharmacology:JNK-IN-8 is a potent and selective irreversible JNK inhibitor (IC50s=4.67, 18.7 and 0.98 nM for JNK1, 2 and 3 respectively).1 JNK blockade with JNK-IN-8 overcomes PD-L1-mediated resistance to chemotherapy in colorectal cancer.2 Improves ARDS-induced cognitive impairment by inhibition of JNK/NF-kB-mediated NLRP3 inflammasome activation.3
分子式:C29H29N7O2
分子量:507.6
溶剂:DMSO (45 mg/ml)
性状:Pale yellow solid
存储:-20°C
Activity (short version):JNK inhibitor
Function / Pharmacology:JNK-IN-8 is a potent and selective irreversible JNK inhibitor (IC50s=4.67, 18.7 and 0.98 nM for JNK1, 2 and 3 respectively).1 JNK blockade with JNK-IN-8 overcomes PD-L1-mediated resistance to chemotherapy in colorectal cancer.2 Improves ARDS-induced cognitive impairment by inhibition of JNK/NF-kB-mediated NLRP3 inflammasome activation.3
