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TGX-221
- 英文名称：TGX-221
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11404
- cas：663619-89-4
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-10-28
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11404 |
| 用途 | 科研检测 |
| 英文名称 | TGX-221 |
| 包装规格 | 1MG |
| CAS编号 | 663619-89-4 |
| 别名 | TGX-221 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C21H24N4O2
分子量:364.45
溶剂:DMSO (10 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Potent and selective PI3K? inhibitor
Function / Pharmacology:TGX-221 is a potent (IC50 = 5 nM) and selective (1000-fold over p110α and p110γ) inhibitor of PI3-kinase isoform p110?.1 Displays anti-thrombotic activity without affecting bleeding time.1,2 It significantly inhibited tumorigenesis in VHL, SETD2, PTEN, and CDKN2A mutated clear cell renal cell carcinoma.3 TGX-221 induced apoptosis in glioblastoma cells and inhibited cell migration and invasion.4
分子式:C21H24N4O2
分子量:364.45
溶剂:DMSO (10 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Potent and selective PI3K? inhibitor
Function / Pharmacology:TGX-221 is a potent (IC50 = 5 nM) and selective (1000-fold over p110α and p110γ) inhibitor of PI3-kinase isoform p110?.1 Displays anti-thrombotic activity without affecting bleeding time.1,2 It significantly inhibited tumorigenesis in VHL, SETD2, PTEN, and CDKN2A mutated clear cell renal cell carcinoma.3 TGX-221 induced apoptosis in glioblastoma cells and inhibited cell migration and invasion.4
