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Fruquintinib
- 英文名称:Fruquintinib
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11405
- cas:1194506-26-7
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-04-30
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11405 |
用途 | 科研检测 |
英文名称 | Fruquintinib |
包装规格 | 1MG |
CAS编号 | 1194506-26-7 |
别名 | Fruquintinib |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C21H19N3O4
分子量:393.40
溶剂:DMSO (5 mg/ml)
性状:White soliod
存储:-20°C
Activity (short version):VEGFR kinase inhibitor
Function / Pharmacology:Fruquintinib is a potent and highly selective inhibitor of VEGFR kinase (IC50’s: VEGFR1= 33 nM, VEGFR2 = 35 nM, VEGFR3 = 0.5 nM).1 It potently inhibited VEGF/VEGFR signaling and cell proliferation in HUVECs and HLECs and prevented angiogenesis in vitro. Fruquintinib is currently is several clinical trials against metastatic colorectal cancer2 and nonsquamous non-small-cell lung cancer3.
分子式:C21H19N3O4
分子量:393.40
溶剂:DMSO (5 mg/ml)
性状:White soliod
存储:-20°C
Activity (short version):VEGFR kinase inhibitor
Function / Pharmacology:Fruquintinib is a potent and highly selective inhibitor of VEGFR kinase (IC50’s: VEGFR1= 33 nM, VEGFR2 = 35 nM, VEGFR3 = 0.5 nM).1 It potently inhibited VEGF/VEGFR signaling and cell proliferation in HUVECs and HLECs and prevented angiogenesis in vitro. Fruquintinib is currently is several clinical trials against metastatic colorectal cancer2 and nonsquamous non-small-cell lung cancer3.