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LDN-192960 HCl
- 英文名称:LDN-192960 HCl
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11432
- cas:184582-62-5
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-04-30
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11432 |
用途 | 科研检测 |
英文名称 | LDN-192960 HCl |
包装规格 | 1MG |
CAS编号 | 184582-62-5 |
别名 | LDN-192960 HCl |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C18H20N2O2S·2HCl
分子量:401.35
溶剂:DMSO (>25 mg/ml) Water (2 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):Haspin and DYRK2/3 inhibitor
Function / Pharmacology:LDN-192960 is a potent inhibitor of Haspin (IC50 = 10 nM), DYRK2 (IC50 = 2 nM), and DYRK3 (IC50 = 19 nM).1,2 It induced cytotoxicity and growth inhibition in multiple myeloma and triple negative breast cancer cells and triple negative breast cancer mouse allo/xenografts via partial inhibition of 26S proteasome activity.3
分子式:C18H20N2O2S·2HCl
分子量:401.35
溶剂:DMSO (>25 mg/ml) Water (2 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):Haspin and DYRK2/3 inhibitor
Function / Pharmacology:LDN-192960 is a potent inhibitor of Haspin (IC50 = 10 nM), DYRK2 (IC50 = 2 nM), and DYRK3 (IC50 = 19 nM).1,2 It induced cytotoxicity and growth inhibition in multiple myeloma and triple negative breast cancer cells and triple negative breast cancer mouse allo/xenografts via partial inhibition of 26S proteasome activity.3