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LDN-192960 HCl
- 英文名称：LDN-192960 HCl
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11432
- cas：184582-62-5
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-12
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11432 |
| 用途 | 科研检测 |
| 英文名称 | LDN-192960 HCl |
| 包装规格 | 1MG |
| CAS编号 | 184582-62-5 |
| 别名 | LDN-192960 HCl |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C18H20N2O2S·2HCl
分子量:401.35
溶剂:DMSO (>25 mg/ml) Water (2 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):Haspin and DYRK2/3 inhibitor
Function / Pharmacology:LDN-192960 is a potent inhibitor of Haspin (IC50 = 10 nM), DYRK2 (IC50 = 2 nM), and DYRK3 (IC50 = 19 nM).1,2 It induced cytotoxicity and growth inhibition in multiple myeloma and triple negative breast cancer cells and triple negative breast cancer mouse allo/xenografts via partial inhibition of 26S proteasome activity.3
分子式:C18H20N2O2S·2HCl
分子量:401.35
溶剂:DMSO (>25 mg/ml) Water (2 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):Haspin and DYRK2/3 inhibitor
Function / Pharmacology:LDN-192960 is a potent inhibitor of Haspin (IC50 = 10 nM), DYRK2 (IC50 = 2 nM), and DYRK3 (IC50 = 19 nM).1,2 It induced cytotoxicity and growth inhibition in multiple myeloma and triple negative breast cancer cells and triple negative breast cancer mouse allo/xenografts via partial inhibition of 26S proteasome activity.3
