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UZH2
- 英文名称:UZH2
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11437
- cas:2756566-45-5
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-04-30
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11437 |
用途 | 科研检测 |
英文名称 | UZH2 |
包装规格 | 1MG |
CAS编号 | 2756566-45-5 |
别名 | UZH2 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C27H37F2N7O
分子量:513.64
溶剂:DMSO (>25 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):METTL3 inhibitor
Function / Pharmacology:UZH2 (2756566-45-5) is a potent (IC50 = 5 nM) and selective (against METTL1 and METTL16) inhibitor of the RNA methyltransferase METTL3, a key component of the writer complex targeting N6-methyladenosine (m6A), the most common RNA modification. It was able to impair cell growth (GI50 = 12 μM) in MOLM-13 cancer cells (AML).
分子式:C27H37F2N7O
分子量:513.64
溶剂:DMSO (>25 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):METTL3 inhibitor
Function / Pharmacology:UZH2 (2756566-45-5) is a potent (IC50 = 5 nM) and selective (against METTL1 and METTL16) inhibitor of the RNA methyltransferase METTL3, a key component of the writer complex targeting N6-methyladenosine (m6A), the most common RNA modification. It was able to impair cell growth (GI50 = 12 μM) in MOLM-13 cancer cells (AML).