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SR-717
- 英文名称：SR-717
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11438
- cas：2375421-09-1
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-04-30
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11438 |
| 用途 | 科研检测 |
| 英文名称 | SR-717 |
| 包装规格 | 1MG |
| CAS编号 | 2375421-09-1 |
| 别名 | SR-717 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C15H8F2N5O3·Li
分子量:381.27
溶剂:DMSO (>25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):STING agonist
Function / Pharmacology:Cell permeable and exceptionally selective STING agonist (IC50 = 7.8 μM). It displayed robust antitumor activity in B16.F10 melanoma and MC38 colorectal adenocarcinoma mouse models. SR-717 promoted the activation of CD8+ T, natural killer, and dendritic cells as well as promoting antigen cross-priming. It was able to induce PD-L1 expression in THP1 cells and in primary human PBMC’s.
分子式:C15H8F2N5O3·Li
分子量:381.27
溶剂:DMSO (>25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):STING agonist
Function / Pharmacology:Cell permeable and exceptionally selective STING agonist (IC50 = 7.8 μM). It displayed robust antitumor activity in B16.F10 melanoma and MC38 colorectal adenocarcinoma mouse models. SR-717 promoted the activation of CD8+ T, natural killer, and dendritic cells as well as promoting antigen cross-priming. It was able to induce PD-L1 expression in THP1 cells and in primary human PBMC’s.
