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FB23-2
- 英文名称：FB23-2
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11439
- cas：2243736-45-8
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-04-30
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11439 |
| 用途 | 科研检测 |
| 英文名称 | FB23-2 |
| 包装规格 | 1MG |
| CAS编号 | 2243736-45-8 |
| 别名 | FB23-2 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C18H15Cl2N3O3
分子量:392.24
溶剂:DMSO (20 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):FTO inhibitor
Function / Pharmacology:FB23-2 is an inhibitor (IC50 = 2.6 μM) of the mRNA m6A demethylase fat-mass- and obesity-associated protein (FTO).1 Displays significant anti-proliferative activity in NB4 (IC50 = 0.8 μM) and MONOMAC6 (IC50 = 1.5 μM) cells. Selective against the RNA demethylase ALKB5. FB23-2 induced myeloid differentiation and apoptosis in acute myeloid leukemia cells. FB23-2 suppressed the proliferation and migration of hepatocellular carcinoma cells via suppressing the expression of the kinase ERBB3 and human tubulin beta class Iva (TUBB4A).2
分子式:C18H15Cl2N3O3
分子量:392.24
溶剂:DMSO (20 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):FTO inhibitor
Function / Pharmacology:FB23-2 is an inhibitor (IC50 = 2.6 μM) of the mRNA m6A demethylase fat-mass- and obesity-associated protein (FTO).1 Displays significant anti-proliferative activity in NB4 (IC50 = 0.8 μM) and MONOMAC6 (IC50 = 1.5 μM) cells. Selective against the RNA demethylase ALKB5. FB23-2 induced myeloid differentiation and apoptosis in acute myeloid leukemia cells. FB23-2 suppressed the proliferation and migration of hepatocellular carcinoma cells via suppressing the expression of the kinase ERBB3 and human tubulin beta class Iva (TUBB4A).2
