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Chroman 1
- 英文名称:Chroman 1
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11457
- cas:1273579-40-0
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-04-30
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11457 |
用途 | 科研检测 |
英文名称 | Chroman 1 |
包装规格 | 1MG |
CAS编号 | 1273579-40-0 |
别名 | Chroman 1 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:99% by HPLC;NMR (Conforms)
分子式:C24H28N4O4
分子量:436.51
溶剂:DMSO (>50 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):ROCK II inhibitor / Stem cell cytoprotectant
Function / Pharmacology:Extremely potent inhibitor of Rho kinase II (ROCK-II)1,2 – it displayed greater selectivity and potency compared to Y-27632 (IC50’s: ROCK I = 52 pM/ROCK II = 1 pM; Y-27632 IC50’s: ROCK I = 71 nM/ROCK II = 46 nM)3. Chroman 1, used in conjunction with trans-ISRIB (Cat# 10-1539), Emricasan (Cat# 10-4280), and polyamines (CEPT cocktail), promotes cytoprotective cell survival in human pluripotent stem cells (hPSCs) and was found to superior to Y-27632.3 Chroman 1 is an important new tool in the generation and maintenance of stem cells.
分子式:C24H28N4O4
分子量:436.51
溶剂:DMSO (>50 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):ROCK II inhibitor / Stem cell cytoprotectant
Function / Pharmacology:Extremely potent inhibitor of Rho kinase II (ROCK-II)1,2 – it displayed greater selectivity and potency compared to Y-27632 (IC50’s: ROCK I = 52 pM/ROCK II = 1 pM; Y-27632 IC50’s: ROCK I = 71 nM/ROCK II = 46 nM)3. Chroman 1, used in conjunction with trans-ISRIB (Cat# 10-1539), Emricasan (Cat# 10-4280), and polyamines (CEPT cocktail), promotes cytoprotective cell survival in human pluripotent stem cells (hPSCs) and was found to superior to Y-27632.3 Chroman 1 is an important new tool in the generation and maintenance of stem cells.