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GRL-0617
- 英文名称：GRL-0617
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11480
- cas：1093070-16-6
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-11-03
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11480 |
| 用途 | 科研检测 |
| 英文名称 | GRL-0617 |
| 包装规格 | 1MG |
| CAS编号 | 1093070-16-6 |
| 别名 | GRL-0617 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:99% by HPLC;NMR (Conforms)
分子式:C20H20N2O
分子量:304.39
溶剂:DMSO (>30 mg/ml) Ethanol (>15 mg/ml)
性状:Beige solid
存储:-20°C
Activity (short version):SARS-CoV PLpro inhibitor
Function / Pharmacology:GRL-0617 is a potent (IC50 = 600 nM) noncovalent inhibitor of severe acute respiratory syndrome-coronavirus papain-like protease (SARS-CoV PLpro). GRL0617 inhibited SARS-CoV viral replication in Vero E6 cells with no cytotoxicity (EC50 = 15 μM). Inactive against human DUB-like proteases HAUSP, USP18, UCH-L1, UCH-L3, and PLP2.
分子式:C20H20N2O
分子量:304.39
溶剂:DMSO (>30 mg/ml) Ethanol (>15 mg/ml)
性状:Beige solid
存储:-20°C
Activity (short version):SARS-CoV PLpro inhibitor
Function / Pharmacology:GRL-0617 is a potent (IC50 = 600 nM) noncovalent inhibitor of severe acute respiratory syndrome-coronavirus papain-like protease (SARS-CoV PLpro). GRL0617 inhibited SARS-CoV viral replication in Vero E6 cells with no cytotoxicity (EC50 = 15 μM). Inactive against human DUB-like proteases HAUSP, USP18, UCH-L1, UCH-L3, and PLP2.
