纯度:>98% by TLC;NMR (Conforms)
分子式:C20H13N5
分子量:323.36
溶剂:DMSO (6 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):FSP1 inhibitor
Function / Pharmacology:iFSP1 inhibits ferroptosis suppressor protein 1, inducing ferroptosis.1 iFSP1 synergizes with GPX4 inhibitors to initiate ferroptosis in cancer cells.1 It potently induced ferroptosis, which promoted innate and adaptive anti-tumor immune responses, in human hepatocellular carcinoma cells which overexpress FSP1.2 A useful tool for establishing ferroptotic cells in Alzheimer’s disease models.3