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GKT-137831
- 英文名称:GKT-137831
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11493
- cas:1218942-37-0
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-04-30
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11493 |
用途 | 科研检测 |
英文名称 | GKT-137831 |
包装规格 | 1MG |
CAS编号 | 1218942-37-0 |
别名 | GKT-137831 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C21H19ClN4O2
分子量:394.85
溶剂:DMSO (65 mg/ml)
性状:Pale-yellow solid
存储:-20°C
Activity (short version):NADPH oxidase NOX1/4 inhibitor
Function / Pharmacology:NADPH oxidase, NOX1/4 inhibitor (Ki = 100-150 nM).1 Inhibits erastin-stimulated ROS production.2 Potentiates immunotherapy by overcoming cancer-associated fibroblast- mediated CD8+ T-cell exclusion.3 Reduces ROS production in LPS-stimulated platelets in a mouse model.4 Reduces subarachnoid hemorrhage-induced neuronal death.5 Potent inhibitor of experimental liver fibrosis in mouse models.6
分子式:C21H19ClN4O2
分子量:394.85
溶剂:DMSO (65 mg/ml)
性状:Pale-yellow solid
存储:-20°C
Activity (short version):NADPH oxidase NOX1/4 inhibitor
Function / Pharmacology:NADPH oxidase, NOX1/4 inhibitor (Ki = 100-150 nM).1 Inhibits erastin-stimulated ROS production.2 Potentiates immunotherapy by overcoming cancer-associated fibroblast- mediated CD8+ T-cell exclusion.3 Reduces ROS production in LPS-stimulated platelets in a mouse model.4 Reduces subarachnoid hemorrhage-induced neuronal death.5 Potent inhibitor of experimental liver fibrosis in mouse models.6