纯度:98% by TLC,;NMR (Conforms)
分子式:C19H13NO4
分子量:319.31
溶剂:DMSO (3.19 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):ASK1 inhibitor
Function / Pharmacology:Potent and selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1), Ki = 500 nM.1 Promotes survival of induced pluripotent stem cells.2 Improves neurological function after intracerebral hemorrhage in a mouse model.3 A highly useful inhibitor for probing the involvement of ASK1 in cellular physiology.4,5