菜单 Close 公司首页 公司介绍 公司动态 证书荣誉 联系方式 在线留言
您当前的位置: 网站首页 > 产品展厅 >药物类 >Vacuolin-1
Vacuolin-1
  • 英文名称:Vacuolin-1
  • 品牌:WYTSCI
  • 产地:进口
  • 型号:1MG
  • 货号:WT-AY-B11519
  • cas:351986-85-1
  • 价格: ¥1/mg
  • 发布日期: 2025-04-10
  • 更新日期: 2025-04-30
产品详请
产地 进口
品牌 WYTSCI
货号 WT-AY-B11519
用途 科研检测
英文名称 Vacuolin-1
包装规格 1MG
CAS编号 351986-85-1
别名 Vacuolin-1
纯度 98+%
分子式
是否进口
纯度:>98% by TLC,;NMR (Conforms)
分子式:C26H24IN7O
分子量:577.43
溶剂:DMSO (35 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):PIKfyve inhibitor
Function / Pharmacology:Vacuolin-1 (351986-85-1) inhibits autophagy via inhibition of Ca2+-dependent fusion of lysosomes with the plasma membrane and the release of lysosomal content and has no effect on other membrane-bound organelles.1 It has been shown to block endosome maturation by activating RAB5 which compromises the biogenesis and function of lysosomes including autophagosomal-lysosomal fusion and endosomal-lysosomal degradation.2 It potently inhibits migration, invasion and colony formation of cancer cells (which is linked to endosomal trafficking) and targets capping protein Zβ (CapZβ) in these processes.3 Inhibition of lysosomal maturation was shown to be due to potent inhibition of PIKfyve.4
联系方式
手机:15317051735
Q Q:
二维码扫描访问