纯度:>98% by TLC;NMR (Conforms)
分子式:C26H43N7O2
分子量:485.68
溶剂:DMSO (50 mg/ml)
性状:White to off-white solid
存储:-20°C
Activity (short version):G9a histone methyl transferase inhibitor
Function / Pharmacology:UNC0224 is a potent inhibitor of histone methyltransferases G9a / EHMT2 (IC50 = 15 nM) and GLP / EHMT1 (IC50 ~ 39 nM) but not SET7/9 and SET8.1-3 Has been employed, as part of a small molecule cocktail, to reprogram somatic cells to pluripotent stem cells.4