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ABT-869
- 英文名称：ABT-869
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11533
- cas：796967-16-3
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-04-30
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11533 |
| 用途 | 科研检测 |
| 英文名称 | ABT-869 |
| 包装规格 | 1MG |
| CAS编号 | 796967-16-3 |
| 别名 | ABT-869 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C21H18FN5O
分子量:375.41
溶剂:DMSO (30 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Dual VEGFR and PDGFR kinase inhibitor
Function / Pharmacology:ABT-869 (796967-16-3) ia a structurally novel, potent inhibitor of receptor tyrosine kinases inhibiting VEGFR and PDGFR and related kinases with IC50s= 3, 4, 4, 66, 3 and 14 nM for VEGFR1, VEGFR2, FLT3, PDGFRβ, CSF-1R and KIT respectively.1,2 Protects cells from necroptosis and rescues SIRS mice from TNF-α-induced shock and death.3 Exerts anti-obesity effects by promoting adipocyte browning.4 Inhibits angiogenesis.5
分子式:C21H18FN5O
分子量:375.41
溶剂:DMSO (30 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Dual VEGFR and PDGFR kinase inhibitor
Function / Pharmacology:ABT-869 (796967-16-3) ia a structurally novel, potent inhibitor of receptor tyrosine kinases inhibiting VEGFR and PDGFR and related kinases with IC50s= 3, 4, 4, 66, 3 and 14 nM for VEGFR1, VEGFR2, FLT3, PDGFRβ, CSF-1R and KIT respectively.1,2 Protects cells from necroptosis and rescues SIRS mice from TNF-α-induced shock and death.3 Exerts anti-obesity effects by promoting adipocyte browning.4 Inhibits angiogenesis.5
