纯度:>98% by HPLC;NMR (Conforms)
分子式:C23H25N5O3S
分子量:451.54
溶剂:DMSO (45 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Enhances stem cell survival / Integrin agonist
Function / Pharmacology:Pyrintegrin is a β1-integrin agonist that promotes survival of human embryonic stem cells following enzymatic dissociation by enhancing cell-ECM-mediated integrin activity.1 It induces soft tissue formation from transplanted or endogenous cells via stimulation of adipogenesis and may have potential in soft tissue therapeutic reconstruction and augmentation2, It protects podocytes from LPS-induced injury in vivo3. A very useful tool for exploring the involvement of β1-integrin signaling in cellular physiology.4,5