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AM-580
- 英文名称:AM-580
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11568
- cas:102121-60-8
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-04-30
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11568 |
用途 | 科研检测 |
英文名称 | AM-580 |
包装规格 | 1MG |
CAS编号 | 102121-60-8 |
别名 | AM-580 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C22H25NO3
分子量:351.45
溶剂:DMSO (35 mg/ml) or ethanol (18 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):RARα agonist
Function / Pharmacology:Retinoic acid analog acting as a RARα agonist (Kd = 8 nM).1 Induces or blocks differentiation depending on cell type and environment.2,3 In combination with CHIR-99021 it induces differentiation of human induced pluripotent stem cells (iPSCs) into intermediate mesoderm (80% induction rate in 5 days) capable of forming kidney structures.4 AM-580 exhibits anti-angiogenic activity in vivo, and induces differentiation of acute promyelocytic leukemia cells.5,6
分子式:C22H25NO3
分子量:351.45
溶剂:DMSO (35 mg/ml) or ethanol (18 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):RARα agonist
Function / Pharmacology:Retinoic acid analog acting as a RARα agonist (Kd = 8 nM).1 Induces or blocks differentiation depending on cell type and environment.2,3 In combination with CHIR-99021 it induces differentiation of human induced pluripotent stem cells (iPSCs) into intermediate mesoderm (80% induction rate in 5 days) capable of forming kidney structures.4 AM-580 exhibits anti-angiogenic activity in vivo, and induces differentiation of acute promyelocytic leukemia cells.5,6