纯度:98% by TLC;NMR (Conforms)
分子式:C13H11NO3
分子量:229.24
溶剂:DMSO (35 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Angiogenesis inducer
Function / Pharmacology:Novel small molecule inducer of angiogenesis which has been shown to be useful in tissue engineering applications.1 In a sustained release model, PNF1 promoted ingrowth and expansion of microvascular networks surrounding biomaterial implants.2 Its mechanism of action includes induction of TNF-α followed by TGF-β signaling and subsequent modulation of MMP14 (MT1-MMP) in human microvascular endothelial cells.3,4