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KNK437
- 英文名称：KNK437
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11573
- cas：218924-25-5
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-12
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11573 |
| 用途 | 科研检测 |
| 英文名称 | KNK437 |
| 包装规格 | 1MG |
| CAS编号 | 218924-25-5 |
| 别名 | KNK437 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C13H11NO4
分子量:245.23
溶剂:DMSO (30 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Inhibits HSP70 expression
Function / Pharmacology:Inhibits constitutive and inducible HSP70 expression in non-stressed1 and heat-stressed2 cancer cells. Blocks the geldanamycin-induced induction of HSP70 and inhibition of TGF? signaling.3 Inhibits leukocyte integrin α4?7-mediated adhesion of T cells to mucosal addressin cell adhesion molecule 1 (MAdCAM-1) suggesting that HSP70 is essential for ?7 integrin signalling.4 Suppresses morphine analgesic tolerance in a rodent model (100 mg/Kg).5
分子式:C13H11NO4
分子量:245.23
溶剂:DMSO (30 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Inhibits HSP70 expression
Function / Pharmacology:Inhibits constitutive and inducible HSP70 expression in non-stressed1 and heat-stressed2 cancer cells. Blocks the geldanamycin-induced induction of HSP70 and inhibition of TGF? signaling.3 Inhibits leukocyte integrin α4?7-mediated adhesion of T cells to mucosal addressin cell adhesion molecule 1 (MAdCAM-1) suggesting that HSP70 is essential for ?7 integrin signalling.4 Suppresses morphine analgesic tolerance in a rodent model (100 mg/Kg).5
