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TPCA-1
- 英文名称：TPCA-1
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11574
- cas：507475-17-4
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-04-30
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11574 |
| 用途 | 科研检测 |
| 英文名称 | TPCA-1 |
| 包装规格 | 1MG |
| CAS编号 | 507475-17-4 |
| 别名 | TPCA-1 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C12H10FN3O4S
分子量:229.29
溶剂:DMSO (30 mg/ml)
性状:Pale yellow solid
存储:-20°C
Activity (short version):Selective inhibitor of IκB kinase 2 (IKK2)
Function / Pharmacology:Selective inhibitor of IκB kinase 2 (IKK2) (IC50 = 17.9 nM).1 Inhibits production of pro-inflammatory cytokines in arthritis and other animal models of inflammation.1,2 Also attenuates NLRP3 inflammasome activation in THP-1 myeloid cells, and suppresses IL1β-induced proliferation, migration, and invasion of HeLa cells.3,4 Continuous exposure to TPCA-1 promotes expansion of hematopoietic stem/progenitor cells (HSPCs) via improved glycolysis and limited ROS production.5
分子式:C12H10FN3O4S
分子量:229.29
溶剂:DMSO (30 mg/ml)
性状:Pale yellow solid
存储:-20°C
Activity (short version):Selective inhibitor of IκB kinase 2 (IKK2)
Function / Pharmacology:Selective inhibitor of IκB kinase 2 (IKK2) (IC50 = 17.9 nM).1 Inhibits production of pro-inflammatory cytokines in arthritis and other animal models of inflammation.1,2 Also attenuates NLRP3 inflammasome activation in THP-1 myeloid cells, and suppresses IL1β-induced proliferation, migration, and invasion of HeLa cells.3,4 Continuous exposure to TPCA-1 promotes expansion of hematopoietic stem/progenitor cells (HSPCs) via improved glycolysis and limited ROS production.5
