纯度:>98% by TLC;NMR (Conforms)
分子式:C9H18N6
分子量:210.29
溶剂:DMSO (40 mg/ml)
性状:White solid
存储:RT
Activity (short version):GPX4 inhibitor; Ferroptosis inducer
Function / Pharmacology:Induces ferroptosis by inhibiting glutathione peroxidase 4 (GPX4) which causes accumulation of lipid hydroperoxides.1 Ferroptosis induction may be its mechanism of action as a cancer chemotherapeutic.2 Clinically useful agent for ovarian cancer.3,4