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STF-118804
- 英文名称:STF-118804
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11583
- cas:894187-61-2
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-04-30
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11583 |
用途 | 科研检测 |
英文名称 | STF-118804 |
包装规格 | 1MG |
CAS编号 | 894187-61-2 |
别名 | STF-118804 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C25H23N3O4S
分子量:461.54
溶剂:DMSO (47 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):NAMPT inhibitor
Function / Pharmacology:Potent and selective next generation inhibitor of nicotinamide phosphoribosyl transferase (NAMPT), inhibiting NAD+ biosynthesis from nicotinamide.1 It reduced the viability of most B-ALL cells with high potency (low nM range), eliminates leukemia stem cells from mouse bone marrow, and induces regression of ALL xenografts.1 It induces apoptosis and reduced neuroblastoma stem cell neurosphere formation in high-risk neuroblastoma cell lines.2 STF-118804 reduces the growth of pancreatic ductal adenocarcinoma cells.3
分子式:C25H23N3O4S
分子量:461.54
溶剂:DMSO (47 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):NAMPT inhibitor
Function / Pharmacology:Potent and selective next generation inhibitor of nicotinamide phosphoribosyl transferase (NAMPT), inhibiting NAD+ biosynthesis from nicotinamide.1 It reduced the viability of most B-ALL cells with high potency (low nM range), eliminates leukemia stem cells from mouse bone marrow, and induces regression of ALL xenografts.1 It induces apoptosis and reduced neuroblastoma stem cell neurosphere formation in high-risk neuroblastoma cell lines.2 STF-118804 reduces the growth of pancreatic ductal adenocarcinoma cells.3