纯度:>98% by HPLC;NMR (Conforms)
分子式:C29H31F3N6O3
分子量:568.6
溶剂:DMSO (30 mg/ml)
性状:Off-white to beige solid
存储:-20°C
Activity (short version):Stimulates pancreatic beta-cell proliferation
Function / Pharmacology:Stimulates human β-cell proliferation both in a dispersed islet proliferation assay and in intact human cultures.1 It has been shown to induce both α- and β-cell proliferation.2 May lead to the development of new therapeutics for diabetes.3 Induces adult hippocampal neurogenesis correlating with its antidepressant effect in a rat model of chronic unpredictable mild stress-induced depression.4 Has been used together with TTNPB and azakenpaullone, as a defined chemical cocktail to induce mouse totipotent stem cells.5 Cell permeable.