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TTK21
- 英文名称：TTK21
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11586
- cas：709676-56-2
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-04-30
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11586 |
| 用途 | 科研检测 |
| 英文名称 | TTK21 |
| 包装规格 | 1MG |
| CAS编号 | 709676-56-2 |
| 别名 | TTK21 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C17H15ClF3NO2
分子量:357.76
溶剂:DMSO (50 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):CBP/p300 histone acetyltransferase activator
Function / Pharmacology:TTK21 (709676-56-2) is a novel activator of CBP/p300 acetyl transferases.1 When TTK21 is conjugated to glucose-based carbon nanospheres (CSP) it is nontoxic and is BBB permeable. CSP-TTK21, upon intraperitoneal administration to mice, acetylated histones in the hippocampus and frontal cortex and increased BDNF levels.1 It reinstated plasticity and memory in a tauopathy mouse model2, ameliorated Aβ-impaired long term potentiation3 and promoted axon growth, sprouting and synaptic plasticity in chronic experimental spinal cord injury4.
分子式:C17H15ClF3NO2
分子量:357.76
溶剂:DMSO (50 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):CBP/p300 histone acetyltransferase activator
Function / Pharmacology:TTK21 (709676-56-2) is a novel activator of CBP/p300 acetyl transferases.1 When TTK21 is conjugated to glucose-based carbon nanospheres (CSP) it is nontoxic and is BBB permeable. CSP-TTK21, upon intraperitoneal administration to mice, acetylated histones in the hippocampus and frontal cortex and increased BDNF levels.1 It reinstated plasticity and memory in a tauopathy mouse model2, ameliorated Aβ-impaired long term potentiation3 and promoted axon growth, sprouting and synaptic plasticity in chronic experimental spinal cord injury4.
