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SU9516
- 英文名称：SU9516
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11589
- cas：377090-84-1
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-04-30
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11589 |
| 用途 | 科研检测 |
| 英文名称 | SU9516 |
| 包装规格 | 1MG |
| CAS编号 | 377090-84-1 |
| 别名 | SU9516 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C13H11N3O2
分子量:241.25
溶剂:DMSO (25 mg/ml)
性状:Orange solid
存储:-20°C
Activity (short version):CDK inhibitor (pan-specific)
Function / Pharmacology:Cyclin-dependent kinase inhibitor, IC50s= 0.02-0.03, 0.04-0.2, 0.2-1.7 and 0.9 μM for cdk2, cdk1, cdk4, cdk9 respectively.1,2 Inhibits phosphorylation of retinoblastoma protein pRb, causing enhanced pRb/E2f complex formation, cell cycle arrest at G1 and G2-M and apoptosis.3 Down-regulates antiapoptotic protein Mcl-1 expression resulting in mitochondrial injury and cell death.4 Inhibits epithelial-mesenchymal transition (IC50=1.21 μM) a crucial pathological event in tumor cell budding and metastasis.5 Cell permeable.
分子式:C13H11N3O2
分子量:241.25
溶剂:DMSO (25 mg/ml)
性状:Orange solid
存储:-20°C
Activity (short version):CDK inhibitor (pan-specific)
Function / Pharmacology:Cyclin-dependent kinase inhibitor, IC50s= 0.02-0.03, 0.04-0.2, 0.2-1.7 and 0.9 μM for cdk2, cdk1, cdk4, cdk9 respectively.1,2 Inhibits phosphorylation of retinoblastoma protein pRb, causing enhanced pRb/E2f complex formation, cell cycle arrest at G1 and G2-M and apoptosis.3 Down-regulates antiapoptotic protein Mcl-1 expression resulting in mitochondrial injury and cell death.4 Inhibits epithelial-mesenchymal transition (IC50=1.21 μM) a crucial pathological event in tumor cell budding and metastasis.5 Cell permeable.
